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RIKEN BioResource Center Mouse E-mail Message   No. 49
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  The RIKEN BioResource Center (BRC) provides you the most up-to-date
information such as newly deposited mouse strains.


=======  content  ======================================================
- Special topic: Mouse of the Month "Drs KO Mouse"
- "IMPORTANT" Request to Users
- Newly deposited mouse strains
- Newly available mouse strains
- Mouse strains for freeze preservation
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|  Special topic: Mouse of the Month    June 2008
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  Drs KO Mouse : A Key Molecule for Tumor Suppression

    Depositor: Dr. Hirokazu Inoue (Shiga Medical University)
  
    RBRC02435 B6.Cg-Srpx<tm1Hzi>

    The Drs gene is originally found as a novel suppressor of v-src
    transformation. The Drs gene expresses in most normal tissues,
    however the expression is completely downregulated in a variety of
    cancer cell lines and tissues. It has been shown that malignant
    tumors such as lymphomas, lung adenocarcinomas and hepatomas were
    generated in about 30% of the Drs KO mice between 7 and 12 months.

    http://www.brc.riken.jp/lab/animal/mailnews/nm200806_01.html

    Mouse of the Month archive
    http://www.brc.riken.jp/lab/animal/en/mouse_of_month_list.shtml


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|  "IMPORTANT" Request to Users
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  Please use the following sentence to clearly indicate the RIKEN BRC
as the source of the BIOLOGICAL RESOURCE in 'Materials and Methods'
of your publication.

Example : ABCDE mouse strain (RBRC12345) was provided by RIKEN BRC
which is participating in the National Bio-Resource Project of the
MEXT, Japan. (RBRC12345: BRC No.)

  The RIKEN BRC is a non-profit institution funded by the Japanese
Government. We are engaged in collecting, maintaining, multiplying,
storing and distributing bioresources, in order to support research and
development in the field of life sciences. The RIKEN BRC has been
providing bioresources not only to scientists in Japan but also to
those in overseas. To be able to continue our service to the
international scientific community, the RIKEN BRC needs to demonstrate
publicly our contribution to the scientific community by disclosing our
user's research publications.

  According to Article 5 of the MTA we would like to request a reprint
of any published research paper that involved the BIOLOGICAL RESOURCE
supplied by RIKEN BRC.


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|  Newly deposited mouse strains
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  These mice have been newly deposited to RIKEN BRC. They will be
available soon after rederivation. We appreciate depositors for their
contributions to the scientific community.

    http://www.brc.riken.jp/lab/animal/mailnews/new0806e.html


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|  Newly available mouse strains
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  These mice just have been rederived into our barrier facility.
These mice are now available for distribution.

    http://www.brc.riken.jp/lab/animal/mailnews/opn0806e.html


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|  Mouse strains for freeze preservation
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  Since enough number of embryos has been preserved, live mice of these
strains will be closed soon. It will take more than 3 months to recover
live mice from frozen stock. Please let us know as soon as possible, if
you plan to use the mice and request them alive.

    http://www.brc.riken.jp/lab/animal/mailnews/freeze0806e.html


________________________________________________________________________
*We hope you enjoyed receiving this message. However, if you would
 rather not receive future e-mails from us, please send an e-mail to
 animal@brc.riken.jp.

*If you have any questions or comments, please send an e-mail to
 animal@brc.riken.jp.

*These contents are subject to change without notice.

*All Rights Reserved.
________________________________________________________________________

RIKEN BioResource Center
Experimental Animal Division
3-1-1 Koyadai, Tsukuba-shi
Ibaraki, 305-0074 Japan
animal@brc.riken.jp
http://www.brc.riken.jp/lab/animal/en/
________________________________________________________________________

2008.06.27