**********************************************************************
RIKEN BioResource Center Mouse E-mail Message   No. 77
**********************************************************************
RIKEN BioResource Center (BRC) is pleased to update you with the latest
information.


=======  contents  =====================================================
- Special topic: Mouse of the Month
  "Visualizing Histone H2A Variants in Chromatin"
- RIKEN BRC has become a member of IMPC
- Announcement: 2011 The Annual Meeting of the Japanese Society for
  Immunology
- Announcement: The 34th Annual Meeting of the Molecular Biology Society
  of Japan
- User publications
- Newly deposited mouse strains
- Newly available mouse strains
- Mouse strains for freeze preservation
========================================================================


+-----------------------------------------------------------------------
|  Special topic: Mouse of the Month    Oct. 2011
+-----------------------------------------------------------------------

  Visualizing Histone H2A Variants in Chromatin
    RBRC05073  B6;B6D2-Tg(CAG-flag-H2A)
    RBRC05074  B6;B6D2-Tg(CAG-flag-H2A.Z)
    RBRC05075  B6;B6D2-Tg(CAG-flag-macroH2A1.2)
    Depositor:Dr. Fugaku Aoki, The University of Tokyo

    http://www.brc.riken.jp/lab/animal/mailnews/nm201110_01.html

  Mouse of the Month archive
    http://www.brc.riken.jp/lab/animal/en/mouse_of_month_list.shtml


+-----------------------------------------------------------------------
|  RIKEN BRC has become a member of IMPC
+-----------------------------------------------------------------------

  An international project to create one of the largest libraries of
mammalian genetic function data has launched on 29th September 2011.
  The International Mouse Phenotyping Consortium (IMPC) is building a
library of mammalian gene function which will describe the function of
every gene in the mouse genome. Around 99 per cent of the genes in a
mouse have an equivalent gene in humans. By understanding the function
of all the genes within the mouse, scientists can improve their
understanding of the role that genes play in human diseases such as
heart disease and diabetes.
  RIKEN BRC has become a member of IMPC

Read more
    Library of gene function will speed up disease research


+-----------------------------------------------------------------------
|  Announcement: 2011 The Annual Meeting of the Japanese Society for
|  Immunology
+-----------------------------------------------------------------------

  2011 The Annual Meeting of the Japanese Society for Immunology will be
held at Makuhari Messe Chiba from November 27 (Sun.) to 29 (Tue.). It is
our pleasure to invite you to visit our booth No. 64 in the
International Exhibition Hall 8.

2011 The Annual Meeting of the Japanese Society for Immunology
    http://wwwsoc.nii.ac.jp/jsi2/jsi40/english/index.html


+-----------------------------------------------------------------------
|  Announcement: The 34th Annual Meeting of the Molecular Biology
|  Society of Japan
+-----------------------------------------------------------------------

  The 34th Annual Meeting of the Molecular Biology Society of Japan will
be held at Pacifico Yokohama from December 13 (Tue.) to 16 (Fri.). We
are pleased to welcome you on the special exhibition booth "National
BioResource Project (NBRP)".

The 34th Annual Meeting of the Molecular Biology Society of Japan
    http://www.aeplan.co.jp/mbsj2011/english/index.html


+-----------------------------------------------------------------------
|  User publications
+-----------------------------------------------------------------------

  The following publications have been newly reported by users. We are
honored to continue serving the scientific community by introducing new
publications. Therefore, we look forward to receiving your publications
too.

RBRC00821  Tg(deGFP)18Imeg
Takehara T, Teramura T, Onodera Y, Hamanishi C, Fukuda K. Reduced
oxygen concentration enhances conversion of embryonic stem cells to
epiblast stem cells. Stem Cells Dev. 2011 Aug 23.

http://www.ncbi.nlm.nih.gov/pubmed/21861689?ordinalpos=abstruct

RBRC00858  IRF-3 knockout mouse/ C57BL/6J
RBRC01420  IRF-7 knockout mouse/ C57BL/6J
Prantner D, Sikes JD, Hennings L, Savenka AV, Basnakian AG, Nagarajan UM.
Interferon Regulatory Transcription Factor 3 Protects Mice from Uterine
Horn Pathology during Chlamydia muridarum Genital Infection. Infect
Immun.;79(10):3922-33, 2011.
http://www.ncbi.nlm.nih.gov/pubmed/21788382?ordinalpos=abstruct

RBRC00886  Tg(acro3-EGFP)/Osb01
Sato T, Katagiri K, Gohbara A, Inoue K, Ogonuki N,Ogura A, Kubota Y,
Ogawa T. In vitro production of functional sperm in cultured neonatal
mouse testes. Nature.;471(7339):504-7, 2011.
http://www.ncbi.nlm.nih.gov/pubmed/21430778?ordinalpos=abstruct

RBRC00886  Tg(acro3-EGFP)01Osb
Sato T, Katagiri K, Yokonishi T, Kubota Y, Inoue K, Ogonuki N, Matoba S,
Ogura A, Ogawa T. In vitro production of fertile sperm from murine
spermatogonial stem cell lines. Nat Commun.;2:472, 2011.
http://www.ncbi.nlm.nih.gov/pubmed/21915114?ordinalpos=abstruct

RBRC01390  Nrf2 knockout mouse/C57BL6J
Chartoumpekis DV,Ziros PG, Psyrogiannis AI, Papavassiliou AG,
Kyriazopoulou VE, Sykiotis GP, Habeos IG. Nrf2 Represses FGF21 During
Long-Term High-Fat Diet-Induced Obesity in Mice. Diabetes.;60(10):2465-
73, 2011.
http://www.ncbi.nlm.nih.gov/pubmed/21852674?ordinalpos=abstruct

RBRC01390  Nrf2 knockout mouse/C57BL6J
Bae SH, Sung SH,Cho EJ, Lee SK, Lee HE, Woo HA, Yu DY, Kil IS, Rhee SG.
Concerted action of sulfiredoxin and peroxiredoxin I protects against
alcohol-induced oxidative injury in mouse liver.Hepatology.,53(3):945-53,
2011.
http://www.ncbi.nlm.nih.gov/pubmed/21319188?ordinalpos=abstruct


+-----------------------------------------------------------------------
|  Newly deposited mouse strains
+-----------------------------------------------------------------------

  The following mice have been newly deposited into RIKEN BRC and
will be available shortly after rederivation.
We appreciate the contributions of the depositors to the scientific
community.

  Dr. Fugaku Aoki, The University of Tokyo
    RBRC05073  B6;B6D2-Tg(CAG-flag-H2A)
    RBRC05074  B6;B6D2-Tg(CAG-flag-H2A.Z)
    RBRC05075  B6;B6D2-Tg(CAG-flag-macroH2A1.2)

  Dr. Masayoshi Imagawa, Nagoya City University Faculty of
Pharmaceutical Sciences
    RBRC05142  B6.126S2-Fad158<tm1Maim>/3Maim
    RBRC05143  B6.126S2-Fad158<tm1Maim>/7Maim

  Dr. Itaru Imayoshi, Institute for Virus Research, Kyoto University
    RBRC05150  B6;129S6-Gt(ROSA)26Sor<tm1(CAG-eNpHR2/EYFP)Imayo>
    RBRC05151  B6;129S6-Gt(ROSA)26Sor<tm1.1(CAG-eNpHR2/EYFP)Imayo>
    RBRC05152  B6;129S6-Gt(ROSA)26Sor<tm1.2(CAG-eNpHR2/EYFP)Imayo>

  Dr. Yasuhisa Matsui, Institute of Development, Aging and Cancer,
Tohoku University
    RBRC05144  B6.B6D2-Tg(Ifitm3-EGFP)3.0GYmat
    RBRC05145  B6.129P2-Prdm9<tm1Ymat>

  Dr. Tamio Ohno, Nagoya University
    RBRC05182  A.SM-(D11Nds1-D11Mit48)
    RBRC05183  A.SM-(D11Mit122-D11Mit48)
    RBRC05184  A.SM-(D11Mit10-D11Mit48)

  Dr. Michisuke Yuzaki, Keio University
    RBRC05061  STOCK Grid2<tm1Mim> Tg(Pcp2-Grid2*Q618R)1Yuza

  RIKEN CDB, Research Promotion Division, RIKEN Kobe Institute
    RBRC05065  B6.B6CB-Sox1<tm1(cre)Take>

    http://www.brc.riken.jp/lab/animal/mailnews/new1109e.html

  Dr. Colmenares Clemencia, Cleveland Clinic Foundation
    RBRC01055  Ski Knockout mouse

  Dr. Takahisa Furukawa, Osaka Bioscience Institute
    RBRC05138  129S6-Trpm1<tm1Tfur>

  Dr. Yoichiro Iwakura, The Institute of Medical Science, The
University of Tokyo
    RBRC04903  C;129X1-Ifng<tm1Yiw>
    RBRC04904  B6;129P2-Cxcr4<tm1Yiw>
    RBRC04905  C;129P2(Cg)-Cxcr4<tm1Yiw> Tg(Lck-cre)1Jtak
    RBRC04907  C.C3B6-Tg(HTLV-I/LTR-pX)647Yiw
    RBRC04918  B6;129S2-Il6<tm1Kopf>
    RBRC04919  C;129S2-Il6<tm1Kopf>
    RBRC04920  B6;129S2-Il4<tm1Kopf>
    RBRC05090  B6;129P2-Il17f<tm1Yiw>
    RBRC05092  B6;129P2-Il17a<tm2Yiw> Il17f<tm1Yiw>
    RBRC05094  B6;129P2-Clec7a<tm1Yiw>
    RBRC05108  C;129P2-Ab124611<tm1Yiw>

  Dr. Yasuhisa Matsui, Institute of Development, Aging and Cancer,
Tohoku University
    RBRC03626  B6.B6D2-Tg(EF1A-BCL2)1Ymat

  Dr. Tamio Ohno, Nagoya University
    RBRC05178  A.SM-(D11Mit106-D11Mit163)

  Dr. Junko Takita, The university of tokyo hospital
    RBRC05203  C57BL/6-Tg(TH-ALK*F1174L)5Homy
    RBRC05235  C57BL/6-Tg(TH-ALK*F1174L)9Homy

  RIKEN CDB, Research Promotion Division, RIKEN Kobe Institute
    RBRC05191  Slc22a17:BOCT(-) (Acc.No.CDB0751K)
    RBRC05196  Slc22a17:BOCT(-)#29 (Acc.No.CDB0751K-2)

    http://www.brc.riken.jp/lab/animal/mailnews/new1110e.html


+-----------------------------------------------------------------------
|  Newly available mouse strains
+-----------------------------------------------------------------------

  The following mice have recently been rederived into our barrier
facility and are now available for distribution.

    RBRC04851  B6C3(129)-Tg(NDE-hsp-Alk4DN,lacZ)1Hmd
    RBRC04852  B6C3(129)-Tg(NDE-hsp-Smad3DN,lacZ)1Hmd
    RBRC04856  C3H/HeJmsHir
    RBRC04857  C57BL/10JMsHir
    RBRC04858  B10.C3-A/Hir
    RBRC04842  C57BL/6N-Tg(Lck-Bhlhe40)1Homy
    RBRC02824  B6;B6D2-Tg(MLC-Wnt4)L202Mni
    RBRC02597  Hes7-Cre (Acc. No. CDB0551T)
    RBRC04742  C.B6CB-Ltb4r2<tm1Tksh>
    RBRC04738  B6.Cg-Tg(Lck-cre)1Jtak

    http://www.brc.riken.jp/lab/animal/mailnews/opn1109e.html

    RBRC03899  STOCK Ephb1<tm1Cmn> Ephb2<tm1Paw>
               Ephb3<tm1Kln> EphB6<tm2Tom>
    RBRC04841  B6N.129P2-Bhlhe40<tm1Homy>
    RBRC04885  B6;129S4-Cacna1e<tm1Ttan>

    http://www.brc.riken.jp/lab/animal/mailnews/opn1110e.html


+-----------------------------------------------------------------------
|  Mouse strains for freeze preservation
+-----------------------------------------------------------------------

  Since a sufficient number of embryos have been preserved, live mice of
the following strains will be discontinued soon.
It will take more than 3 months to recover live mice from frozen stock.
Therefore, please inform us as soon as possible if you plan to use the
mice and request them alive.

    RBRC04055  C57BL/6N-Tg(BGLAP-PTN/CAG-EGFP)20Thg
    RBRC04609  B6;129P2-Wnt5a<tm1.1Homy>
    RBRC02435  B6.Cg-Srpx<tm1Hzi>
    RBRC04360  C57BL/6J-Tg(hSMA-TRPC6)1
    RBRC04361  C57BL/6J-Tg(hSMA-TRPC6DN)1
    RBRC03073  C57BL/6J-Tg(hSMA-NCX1.3*del)1
    RBRC01190  Evi9/BclIIa Knockout mice
    RBRC04058  C57BL/6-Tg(Nes-d4YFP*)1HOkn
    RBRC01897  Floxed Sox2 mice
    RBRC01260  Xist1loxGFPmice
    RBRC01663  K14-AhR-CA TG mouse line 239
    RBRC02889  D2.B6-Tg(CAG-EGFP)C14-Y01-FM131Osb/Ny

    http://www.brc.riken.jp/lab/animal/mailnews/freeze1109e.html


________________________________________________________________________
*We hope you find the contents of this message of interest. 
 However, if you would prefer to unsubscribe from future e-mails, please
 send an e-mail to animal@brc.riken.jp.

*If you have any questions or comments, please send an e-mail to
 animal@brc.riken.jp.

*Content is subject to change without notice.

*All Rights Reserved.
________________________________________________________________________

RIKEN BioResource Center
Experimental Animal Division
3-1-1 Koyadai, Tsukuba-shi
Ibaraki, 305-0074 Japan
animal@brc.riken.jp
http://www.brc.riken.jp/lab/animal/en/
________________________________________________________________________

2011.11.09