List of tests in modified SHIRPA
Modified SHIRPA (ver 1.04: 2002.3~) Q# Test Identical to original
SHIRPA * 0 1 2 3 4 5 6 1 Coat color - Not tested Normal Diluted Spot(s) Change in color Other - - 2 Hair length - Not tested Normal Alopecia Short Long - - - 3 Hair morphology - Not tested Normal Curly Other - - - - 4 Respiration rate Yes Not tested Gasping, irregular Slow, shallow Normal Hyperventilation - - - 5 Tremor Yes Not tested None Mild Marked - - - - 6 Body position Yes Not tested Completely flat Lying on side Lying prone Sitting or standing Rearing on hind limbs Repeated vertical leaping - 7 Spontaneous activity Yes Not tested None, resting Casual scratching, grooming, slow movement Vigorous scratching, grooming, moderate movement Vigorous, rapid/dart movement Extremely vigorous, rapid/dart movement - - 8 Defecation Yes Not tested Amount of feces - - - - - - 9 Urination Yes Not tested None Present - - - - - 10 Time elapsed before the mouse starts to move after it
dropping onto the floor of the arena (seconds) - Not tested Time elapsed before the mouse starts to move after it
dropping onto the floor of the arena (seconds) - - - - - - 11 Locomotor activity Yes Not tested Number of squares entered by all four feet in 30
seconds. - - - - - - 12 Transfer arousal Yes Not tested Coma Prolonged freeze, then slight movement Extended freeze, then moderate movement Brief freeze (few seconds), then active movement Momentary freeze, then swift movement No freeze, immediate movement Extremely excited ("manic") 13 Piloelection Yes Not tested None Coat stood on end - - - - - 14 Parapebral closure Yes Not tested Eyes wide open Eyes 1/2 closed Eyes closed - - - - 15 Startle response Yes Not tested None Preyer reflex (backward flick of pinnae) Jump less than 1 cm Jump more than 1 cm - - - 16 Gait Yes Not tested Normal Fluid but abnormal Limited movement only Incapacity - - - 17 Pelvic elevation Yes Not tested Markedly flattened Barely touching Normal (3mm elevation) Elevated (more than 3mm elevation) - - - 18 Tail elevation Yes Not tested Dragging Horizontally extended Elevated / Straub Tail - - - - 19 Touch escape Yes Not tested No response Mild (escape response to firm stroke) Moderate (rapid response to light stroke) Vigorous (escape response to approach) - - - 20 Positional passivity Yes Not tested Struggles when held by tail Struggles when held by neck (finger grip, not
scruffed) Struggles when laid supine (on back) Struggles when held by hind limbs No struggle - - 21 Trunk curl Yes Not tested Absent Present - - - - - 22 Limb grasping Yes Not tested Absent Present - - - - - 23 Visual placing Yes Not tested None Upon nose contact Upon vibriassae contact Before vibriassae contact (18mm) Early vigorous extension (25mm) - - 24 Grip strength Yes Not tested None Slight grip, semi-effective Moderate grip, effective Active grip, effective Unusually effective - - 25 Body tone Yes Not tested Flaccid, no return of cavity to normal Slight resistance Extreme resistance, board like - - - - 26 Morphology of head - Not tested Normal Abnormal - - - - - 27 Pinna reflex Yes Not tested None Active retraction, moderately brisk flick Hyperactive, repetitive flick - - - - 28 Pinna morphology (Right) - Not tested Normal Abnormal - - - - - 29 Pinna morphology (Left) - Not tested Normal Abnormal - - - - - 30 Corneal reflex Yes Not tested None Active single eye blinking Multiple eye blinking - - - - 31 Toe pinch Yes Not tested Slight withdrawal Moderate withdrawal, not brisk Brisk, rapid withdrawal Very brisk repeated extension and flexion - - - 32 Body length Yes Not tested mm - - - - - - 33 Tail length - Not tested mm - - - - - - 34 Tail morphology - Not tested Normal kink curl other - - - 35 Lacrimation Yes Not tested None Present - - - - - 36 Whisker morphology - Not tested Normal Abnormal - - - - - 37 Teeth morphology - Not tested - - - - - - - 38 Provoked biting Yes Not tested Absent Present - - - - - 39 Salivation Yes Not tested None Slight margin of sub-maxillary area Wet zone entire sub-maxillary area - - - - 40 Heart rate Yes Not tested Slow, bradycardia Normal Fast, tachycardia - - - - 41 Abdominal tone Yes Not tested Flaccid, no return of cavity to normal Slight resistance Extreme resistance, board like - - - - 42 Skin color Yes Not tested Blanched Pink Bright, deep red flush Dark footpad or pigmentation - - - 43 Limb morphology (Fore-Right) - Not tested Normal polydactyly Ectrodactyly Abnormality in upper limb Other - - 44 Limb morphology (Fore-Left) - Not tested Normal polydactyly Ectrodactyly Abnormality in upper limb Other - - 45 Limb morphology (Hind-Right) - Not tested Normal polydactyly Ectrodactyly Abnormality in upper limb Other - - 46 Limb morphology (Hind-Left) - Not tested Normal polydactyly Ectrodactyly Abnormality in upper limb Other - - 47 Limb tone Yes Not tested No resistance Slight resistance Moderate resistance Marked resistance Extreme resistance - - 48 Wire maneuver Yes Not tested Active grip with hindlimbs Difficulty to grasp with hindlimbs Unable to grasp with hindlimbs Unable to lift hindlegs, falls within seconds Falls immediately - - 49 Righting reflex Yes Not tested No impairment Lands on side Lands on back Fails to right when placed on back - - - 50 Contact righting reflex Yes Not tested Absent Present - - - - - 51 Negative geotaxis Yes Not tested Turns and climbs the grid Turns but then freezes Moves, but fails to turn Does not move within 30 seconds Falls off - - 52 Fear Yes Not tested None Freezes during transfer arousal - - - - - 53 Irritability Yes Not tested None Struggle during supine restraint - - - - - 54 Aggression Yes Not tested None Provoked biting or attack - - - - - 55 Vocalization Yes Not tested None Provoked during handling - - - - - 56 Yes Not tested - - - - - - - 57 Yes Not tested - - - - - - - 58 Body weight (g) Yes Not tested Body weight (g) - - - - - -
Version
histry
Bizarre
Behavior HF Head flicking or head shaking HS Head searching - repetitive H Hallucinating-like animal appears to respond to objects
not present, e.g . visual tracking or fear withdrawal B Compulsive biting - usually of grid floor L Compulsive licking - usually of glass jar SB Self destructive biting - usually of toes with
bleeding P Prancing forelimbs - shifting from one forelimb to
another while slightly turning the body from side to
side UW Upright walking - hind limbs only AW Aimless wandering - slow plodding around with no apparent
purpose C Circling W Waltzing - rapid turning in circles R Retropulsion - animal walks backwards D Spatial disorientation - walking or stumbling into
objects HB Head bobbing
Convulsions a-1 C = Clonic - co-ordinated, unsymmetrical convulsion and
natural, purposeful seemingly movements, e.g. running,
sometimes a-2 Cs = Clonic symmetrical - repetitive symmetrical jerks or
twitches of the limbs a-3 Rn = Running excitement - often accompanied by mild
clonus or leading to severe convulsions a-4 Ch = Champing - clonus of the jaws only a-5 P = Popcorn - seizure where animal repeatedly "pops" into
the air a-6 A = Asphyxia - a terminal clonic or clonic-tonic
convulsion resulting from respiratory failure. b-1 T = Tonic - sustained extension of hindlimbs, usually
preceded by tonic flexion b-2 Op = Opisthotonus - head, body and limbs are rigidly
extended and arched backwards. b-3 Em = Emprosthonus - opposite of Op i.e. extended
forward. c-1 Rr = Rock and roll - animal is prostrate on its back and
rocks from side to side in a seeming effort to right itself,
occasionally rolling over (overshooting) and continuing to
rock again. c-2 Su = Sitting up - sits upright on hindlimbs during the
seizure c-3 Pr = Praying - sitting up seizure in which the forelimbs
are held together or crossed in a position resembling
prayer.
*******Version histry*******
2004.4.1
New shortened version was added.
"V2shirpa"
: This shortened version involves 34 subtests, Q 1, 2, 3, 5, 10, 11, 14, 15, 16, 19, 21, 21, 23, 26, 27, 28, 29, 32, 33, 35, 35, 36, 37, 41, 42, 43, 44, 45, 46, 51, 52, 56, 57, 58. Details of subtests are identical to v1.04
2003.11.1
Multiple shortened versions of Modified SHIRPAcan be mixed by the concept of "SetName". SetName" is recorded with result of each test and used for discrimination of shortened versions.
Following are SetName for the shortened/un-shortened versions.
"BL and BW": This shortened version incvolves only subtests, Q 15, Q 32 and Q 58. Details of subtests are identical to v1.04
"v1.0x Early": This is un-shortened version. Full of subtests was involved. Details of subtests are identical to v1.04
2002.3.8
v1.04: in Q42, "3: dark footpad or pigmentation" was added.
2000.6
v.1
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