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Mouse Name :     M100073     (Obtained from dominant screening)
  Summary : 3 Phenotypes / Genes
Category Phenotype / Gene name Mode of inheritance Inheritance Chr
1 Open Field total activity high Dominant Inherited 6
2 Passive Avoidance convulsion Dominant Inherited Unclear
3 Other abnormal posture Dominant Inherited 6

Information about Founder Mouse Description of Phenotype / Mutation Screening Result Inheritance of Phenotype / Genotype
Link to BRC

Information about Founder Mouse

    Founder name : M100073
Strain   : DBF1
Sex : Female
Born : 2000/09/25
Dead : 2002/12/30

    Parent
Female : DBA/2J
Male (ENU injected) : C57BL/6J (70mg/kg x 3)

Description of Phenotype / Mutation


  Hyperactivity in open-field (3.3 to 7.6SD above the mean). Abnormal hunched back posture. Lose balance in rearing. Hyperactivity in home-cage. Some animals show convulsive seizure after cage-change and/or behavioral testing.


Screening Results

Modified SHIRPA Hematology Urinalysis Clinical Biochemistry PTZ-Seizure Homecage Activity (Behavior)
Open Field (Behavior) Passive Avoidance (Behavior) Hearling Blood Pressure Fundus Anatomy

Inheritance of Phenotype / Genotype

   3 Phenotypes / Genes
Phenotype / Gene name Inheritance No. of inherited / No. of tested Mode of inheritance Chr
1 total activity high Dominant 7 / 31 Inherited 6
2 convulsion Dominant 4 / 31 Inherited Unclear
3 abnormal posture Dominant 7 / 31 Inherited 6

Segregation of Phenotype / Genotype is here

Contact: Knowledge-base@brc.riken.jp
Please read the "Availability of the Mutant Mice".
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